Coronary Artery Disease, Coronary Stenosis, Myocardial Ischemia
Conditions
Keywords
Coronary artery disease, Percutaneous coronary intervention, Coronary artery bypass graft, Medication therapy
Brief summary
The study is to determine the long-term outcome of patients with coronary triple vessels disease (TVD) in the real world of China, by three different treatment strategies: percutaneous coronary intervention (PCI), Coronary artery bypass graft (CABG) or optimal medication therapy (OMT).
Detailed description
About 10,000 participants will be enrolled into this retrospective study. Study coordinators will include both men and women over the age of 18 who had angiographic proved triple-vessel disease in a 15 years long-term. Detailed procedural data will be obtained by the study coordinator and local principal investigator. These data will be entered into the electronic data capture system. Participants will have telephone follow-up interviews conducted by the centralized follow-up center at Fuwai Hospital.
Interventions
None listed
Sponsors
Chinese Academy of Medical Sciences, Fuwai Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Subject has coronary angiography confirmed triple-vessel disease. 2. Subject is ≥ 18 years of age at the time of inclusion. 3. Subject is willing to comply with all protocol-required follow-up evaluation (patient will be followed during 1 month after hospital to assess any complications and clinical status).
Exclusion criteria
1. Subject is participating in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation. 2. Female subjects with a positive quantitative or qualitative pregnancy test, in accordance with hospital policy. 3. Subjects with no way contact by telephone for follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality | Through study completion, an average of 5 year | The mortality due to any cause |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Major adverse cardiac and cerebrovascular event | Through study completion, an average of 5 year | The incidence rate of major adverse cardiac and cerebrovascular event (MACCE), which is a combination of all-cause death, myocardial infarction, stroke and repeat revascularization |
| Myocardial infarction | Through study completion, an average of 5 year | The Incidence rate of myocardial infarction, including ST elevation myocardial infarction and non-ST elevation myocardial infarction |
| Stroke | Through study completion, an average of 5 year | The incidence rate of stroke, including cerebral infarction and hemorrhage |
| Repeat revascularization | Through study completion, an average of 5 year | The incidence rate of repeat revascularization, including target vessel revascularization and non-target vessel revascularization |
Countries
China
Contacts
Primary ContactLei Song, MD
Backup ContactLei Song, MD
Outcome results
None listed