Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs

Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs Using the Integrated Algorithm by Heidelberg Spectralis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02631369

Acronym

CySLO

Enrollment

Registered

2015-12-16

Start date

2015-12-31

Completion date

2017-12-31

Last updated

2018-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trochlear Nerve Diseases

Brief summary

Pre-Study: Evaluation of the inter- and intrarater reliability of the integrated algorithm by Heidelberg Spectralis for measuring cyclotorsion on SLO-fundus fotographs, and assessment of the influence of measuring with or without eye tracker. Study: Comparison of cyclotorsion measurements in patients with forth nerve palsy and in healthy controls on SLO-fundus fotographs using the integrated algorithm by Heidelberg Spectralis

Interventions

DEVICEHeidelberg Spectralis OCT device

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* ≥ 18 years old * best corrected visual acuity ≥ 0.8

Exclusion criteria

* strabismus except for forth nerve palsy * previous strabismus surgery * monocle * best corrected visual acuity ≤ 0.6 * hyperopia or myopia \> 6dpt

Design outcomes

Primary

Measure	Time frame	Description
pre-study: reliability of repeated measurements of excyclotorsion in degrees on SLO-fundus fotographs	3 months	pre-study: inter- and intrarater reliability of the device with or without eye tracker; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis
study: excyclotorsion in degrees on SLO-fundus fotographs	12 months	study: comparison of cyclotorsion measurements in healthy controls compared to patients with forth nerve palsy; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis

Secondary

Measure	Time frame	Description
study: excyclotorsion in degrees on tangent screen, double maddox and fundus photographs	12 months	validation of the cyclotorsion measurement with the Heidelberg Spectralis device against tangent screen \[degrees\], double maddox \[degrees\] and fundus photographs \[degrees\]

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026