The Effect of Succinylated Gelatin on the Blood Viscosity and Oxygen Delivery

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02631356

Enrollment

Registered

2015-12-16

Start date

2015-11-30

Completion date

Unknown

Last updated

2015-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Viscosity

Brief summary

The study is to investigate the effect of succinylated gelatin on the blood viscosity and oxygen delivery in patients during surgeries, so as to have a better understanding of the safety in the use of succinylated gelatin for surgical patients.

Interventions

DRUGRinger's lactate solution

DRUGSuccinylated gelatin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients between the ages of 18 years and 60 years * ASA physical status I and II * surgical procedures requiring general anesthesia with continuous CVP and arterial pressure monitoring

Exclusion criteria

* Patients younger than 16 y or older than 60 y * Body Mass Index (BMI) \<18 or \>30 * Allergy to any of the drugs used * Severe cardiovascular dysfunction * Patient refusal

Design outcomes

Primary

Measure	Time frame
The patient's arterial blood viscosity (mpa.s) as tested by viscometer	up to 5 months (after the infusion of succinylated gelatin )

Secondary

Measure	Time frame
The patient's oxygen delivery index (DO2I) as calculated by Vigileo	up to 5 months (after the infusion of succinylated gelatin )

Countries

China

Contacts

Primary ContactXia Feng, MD. Ph.D.

fengxia@mail.sysu.edu.cn13688877856

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026