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Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

Correlation of Postoperative Vision and Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02628158
Enrollment
91
Registered
2015-12-11
Start date
2013-04-30
Completion date
2015-10-31
Last updated
2015-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epiretinal Membrane

Keywords

Epiretinal membrane

Brief summary

Fundus autofluorescence (FAF) at the macula originates from hyperfluorescence from retinal pigment epithelium (RPE) and blockage of hyperfluorescence by macular pigment. Investigators evaluate whether presence of FAF may correlate to the postoperative visual outcome for epiretinal membrane.

Detailed description

92 eyes with epiretinal membrane were performed vitreous surgery, epiretinal membrane removal and internal limiting membrane (ILM) peeling. Presence of hyperfluorescence in FAF at the macular area and best-corrected visual acuity (BCVA) was evaluated preoperatively and at postoperative 1, 3, and 6 months with ultra-wide angle imaging.

Interventions

PROCEDUREVitrectomy with internal limiting membrane removal

Vitrectomy with removal of epiretinal membrane and internal limiting membrane

Sponsors

Kyorin University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Age
20 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* The inclusion criteria were patients who underwent vitrectomy and internal limiting membrane removal for epiretinal membrane and had followed for more than 6 months.

Exclusion criteria

* The patients with follow-up less than 6 months.

Design outcomes

Primary

MeasureTime frameDescription
Visual acuity before and after surgeryChanges from baseline to 1, 3, 6 monthsVision

Secondary

MeasureTime frameDescription
Presence of fluids autofluorescence at the macular areaChanges from baseline up to 6 monthsFundus autofluorescence

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026