Exercise-induced High-sensitivity Troponin Levels as a Predictor for Obstructive Coronary Artery Disease

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02626806

Acronym

EUROCAD

Enrollment

150

Registered

2015-12-10

Start date

2013-11-30

Completion date

Unknown

Last updated

2015-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

exercise test, HS -troponin, Coronary artery disease

Brief summary

1. To compare hs-TnT levels after a cardiac stress test in patients with vs. patients without CAD 2. To assess the level of post-exercise hs-TnT predicting CAD (using ROC-analysis) 3. To determine the sensitivity, specificity and accuracy of this exercise-induced hsTopT level in predicting CAD, either alone or in relation to traditional patient-related and exercise test-related metrics

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

1. Patients with suspected CAD, planned for diagnostic coronary angiogram 2. Patients with previous revascularization, suspected of recurrent ischemia

Exclusion criteria

1. Congestive cardiomyopathy with LV EF \< 35% 2. Renal failure with eGFR \< 30 ml/min 3. Known structural or severe valvular heart disease 4. Prior CABG 5. Previous ACS \< 6 weeks 6. Known incomplete revascularization after previous PCI 7. Unstable angina or ACS (defined as unstable anginal symptoms + ECG changes or hs-TnT \> 0.053 ng/L)

Design outcomes

Primary

Measure	Time frame
Presence of coronary artery stenosis more than 50%	24 hours

Countries

Belgium

Contacts

Primary ContactDries De Cock, MD

dries.decock@uzleuven.be003216341519

Backup ContactNick Hiltrop, MD

nick.hiltrop@uzleuven.be003216344235

Outcome results