Lumbar Spinal Stenosis
Conditions
Brief summary
This study investigate the utility of continuous oxygen insufflation during fiberoptic bronchoscope-guided intubation. One group receives oxygen via suction channel of fiberoptic bronchoscope during intubation. The other group does not receive oxygen during fiberoptic bronchoscope-guided intubation. Then, the velocity of deoxygenation difference of PaO2(baseline
Detailed description
Fiberoptic bronchoscope-guided intubation is a gold standard for intubation of a patient with anticipating difficult airway. This technique takes several minutes without oxygen supply, which results in hypoxia when it prolonged. If continuous supply of oxygen during procedure improve the oxygenation, we can reduce the risk of hypoxemia and increase the safety margin during procedure.
Interventions
DRUGOxygen
Oxygen is supplied through suction port during bronchoscope-guided intubation.
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* patients who have surgery under general oral endotracheal anesthesia with invasive arterial blood pressure monitoring
Exclusion criteria
* history of lung disease * abnormality in chest x-ray * anticipating difficult intubation * pregnant women * who is unable to understand and agree the consent form
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Velocity of PaO2 decrease | from mask removal to 1st manual ventilation after intubation, up to 5 minute | After administration of anesthetic agents and manual ventilation of 5 minutes, arterial blood sampling is collected. Then bronchoscope-guided intubation performed and arterial blood sample is collected immediately after the intubation completed. Time for intubation (between 1st and 2nd blood sample) is recorded. The difference of PaO2(before & after intubation) is divided by the time taking for intubation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| success of intubation | 300 sec after the beginning of intubation | After 1st trial of intubation, the success of intubation is recorded. If it takes more than 300 sec, it will be considered failure. |
| PaO2 | 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute | arterial blood samples are collected before and after intubation. |
| PaCO2 | 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute | arterial blood samples are collected before and after intubation. |
| pH | 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute | arterial blood samples are collected before and after intubation. |
| visual field | throughout the intubation with bronchoscope, upto 5 minute | Visual field is evaluated by the blinded observer. It is evaluated as followed;excellent, good, poor, impossible |
Countries
South Korea
Outcome results
None listed