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PHENOTYPE. Therapeutic Study in Barcelona

Positive Health Effects of the Natural Outdoor Environment in Typical Populations in Different Regions in Europe. Work Package 4: Therapeutic Study in Barcelona

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02624921
Enrollment
26
Registered
2015-12-09
Start date
2013-10-31
Completion date
2014-01-31
Last updated
2018-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Natural Outdoor Environments, Poor Mental Health

Brief summary

The study aimed to explore therapeutic effects of natural environments. To do so, the investigators evaluated the immediate and sustained changes in several indicators of well-being while people (n=26) with poor mental health were engaged in unconstrained exposures to natural (green, blue) and urban environments. The indicators included: affection, cognition, physiological responses. Each participant was exposed to all environments for a period of 210 minutes between October 2013 and January 2014. During the exposure period, participants were instructed to do what they would usually do in that environment. Before, during (at 30 and 210 minutes) and after each exposure, several psycho-physiological measures were taken: (i) heart rate variability and heart rate using a Holter monitor, (ii) blood pressure using a digital blood pressure monitor, (iii) physical activity using the CalFIT application installed in a Smartphone, (iv) lung function using a portable computerized spirometer, (v) stress level using salivary cortisol samples collected using Salivettes, (vi) affect, perceived restoration and social interactions using questionnaires, (vii) cognitive functioning using the backwards digit-span task test.

Interventions

Participants were transported one day to a urban setting, one day to a green space, one day to a beach. No intervention was done.

Sponsors

Barcelona Institute for Global Health
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* MHI-5 scored in the lower 50th percentile of the Barcelona city PHENOTYPE sample * willing to participate

Exclusion criteria

* no able to walk for 30 minutes at self-directed pace. * with chest, abdomen surgery or heart attack during the last three months. * with retinal detachment or eyes surgery or hospitalized for heart problem during the last month. * with tuberculosis treatment, or respiratory infection during the last three weeks. * being asthmatic or pregnant * using inhaler the 24 hours previous to the study day. * taking medication different from the usual the 24 hours previous to the study day.

Design outcomes

Primary

MeasureTime frame
Change from cognitive functioning at 210 min (backward digit span task)after 210 minutes of exposure to green/blue/urban environment
Change from blood pressure at 30minafter 30 minutes of exposure to green/blue/urban environment
Change from stress level at 30min (salivary cortisol)after 30 of exposure to green/blue/urban environment
Change from affect at 30 min (BRUMS/POMS)after 30 minutes of exposure to green/blue/urban environment
Change from cognitive functioning at 30 min (backward digit span task)after 30 minutes of exposure to green/blue/urban environment
Change from Baseline heart rate variability at 210 minafter 210 minutes of exposure to green/blue/urban environment
Change from Baseline heart rate at 210 minafter 210 minutes of exposure to green/blue/urban environment
Change from blood pressure at 210minafter 210 minutes of exposure to green/blue/urban environment
Change from stress level at 210min (salivary cortisol)after 210 minutes of exposure to green/blue/urban environment
Change from affect at 210 min (BRUMS/POMS)after 210 minutes of exposure to green/blue/urban environment
Change from Baseline heart rate variability at 30 minafter 30 minutes of exposure to green/blue/urban environment
Change from Baseline heart rate at 30 minafter 30 minutes of exposure to green/blue/urban environment

Secondary

MeasureTime frameDescription
perceived restoration 30 (ROS - Korpela's Restoration outcome scale)after 30 minutes of exposure to green/blue/urban environment
subjectively recorded social interactions 30after 30 minutes of exposure to green/blue/urban environmentMeasurement tool developed by the research team
ambient air pollution exposure 30 (PM2.5)During the first 30 minutes of exposure to green/blue/urban environmentMeasured with MicroAthelometer
objectively measured physical activity 210During the first 210 minutes of exposure to green/blue/urban environmentMeasured with a Smartphone application (CalFIT)
perceived restoration 210 (ROS- Korpela's Restoration outcome scale)after 210 minutes of exposure to green/blue/urban environment
subjectively recorded social interactions 210after 210 minutes of exposure to green/blue/urban environmentMeasurement tool developed by the research team
ambient air pollution exposure 210 (PM2.5)During the first 210 minutes of exposure to green/blue/urban environmentMeasured with MicroAthelometer
personal air pollution (CO, NO, NO2)During all the data collection dayPersonal sensors designed and built at Cambridge University, UK (CamPerS)
objectively measured physical activity 30During the first 30 minutes of exposure to green/blue/urban environmentMeasured with a Smartphone application (CalFIT)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026