Premature Birth, Preterm Birth
Conditions
Keywords
Pea Pod, Body composition
Brief summary
The purpose of this study is to gain information that may be useful in helping to figure out better or newer ways to provide nutrition to babies born premature.
Detailed description
Babies born premature weigh significantly less at the time of hospital discharge when compared to babies born at the corresponding age. The researchers in this study believe that the lower body weight at discharge may be due to lower muscle mass. However, there is no such information available for that at this time. It is important to have this information as babies who weigh less than normal at hospital discharge may develop higher blood pressure and higher sugar levels when they are 10-15 years old. By doing this study, researchers will be able to have information about the baby's muscle mass, which will help the researchers to provide better nutrition to babies who are born premature. Researchers will also be able to determine if there are any differences in the muscle/fat mass based on the type of feeding (breast milk alone, formula alone or a combination of breast milk and formula). This information may be beneficial in helping to promote the appropriate type of feeding for babies born premature.
Interventions
DEVICEPEA POD Infant Body Composition System
The non-invasive device used in this study to measure a baby's body composition is a called a Pea Pod. The Pea Pod is a quick, safe, non-invasive and reliable bedside procedure used to measure changes in infant body composition.
Sponsors
Vishal Pandey, M.D.
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
23 Weeks to 42 Weeks
Healthy volunteers
Yes
Inclusion criteria
* Newborns \<32 weeks gestational age, singleton or multiple gestation * 34-36 weeks gestational age newborns * Term healthy infants from uncomplicated pregnancy
Exclusion criteria
* Babies with life threatening illness unlikely to survive * Congenital and chromosomal anomalies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the Fat mass percentage between 36 and 40 weeks in preterm infants | Change in the Fat mass percentage between 36 weeks and 40 weeks corrected age | Body composition as determined by the PEA POD air displacement plathesmography would determine the fat mass percentage and the serial measure of this parameter would determine the changes in the fat mass percentage indicating the quality of growth between 36 and 40 weeks post conceptional age. At 40 weeks corrected age, the fat mass percentage of the premature infants would be compared with ten healthy term infants born to healthy mothers with uncomplicated pregnancies. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of the Fat mass percent between preterm infants at 40 weeks and those born at Term gestation. | 40 weeks corrected age | The Fat mass percentage in preterm infants at the 40 weeks corrected age would be compared with healthy full term infants born following an uncomplicated pregnancy. |
Countries
United States
Outcome results
None listed