Prostate Cancer, Prostatectomy
Conditions
Brief summary
The purpose of this pilot study is to evaluate the feasibility of recruiting African American prostate cancer survivors to a 12 week physical activity intervention study of three arms (aerobics, resistance training, and usual care) through physician referral and community advertisement strategies. In addition, the investigators will investigate the acceptance rate of the intervention and gather preliminary results on the effect of exercise on African American men's urinary and sexual functions. These data can then be used to refine the intervention and its implementation model, and to inform the submission of a larger grant to the National Institutes of Health.
Interventions
OTHERCommunity Health Activities Model Program for Seniors (CHAMPS)
* Physical activity questionnaire for older adults * Asks about activities in the past 4 weeks * 41 questions and asks to notate how long the activity took
OTHERLifetime Total Physical Activity Questionnaire
* Questions about leisure time (27) and household activities (5) * Mark if participated in the activity during the past year, ages 51-65, 35-50, 23-34, and onset of puberty through 21 years
OTHERExpanded Prostate Cancer Index Composite (EPIC)
* Measures urinary and sexual function before and after prostate cancer treatment * 7 questions about urinary function * 9 questions about sexual function
OTHERInternational Physical Activity Prevalence Study Environmental Module
-The 17-item Physical Activity Neighborhood Environment Scale can be used to assess the environmental factors for walking and bicycling in various neighborhoods.
OTHERGodin Leisure-Time Exercise Questionnaire (GLTEQ)
-4 item query of usual leisure time exercise habits
OTHERQuestionnaire regarding behavior/lifestyle changes since diagnosis
OTHER12 week Walking Program
OTHER12 week Resistance Training Program
Sponsors
Washington University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Speaks English * African American * Radical prostatectomy for treatment of prostate cancer within the past 12 months * Cleared by physician to safely participate in a physical exercise program
Exclusion criteria
* Does not speak English * Non-African American * Previously undergone radiation treatment to the pelvis * Previously undergone major pelvic surgery * Known urethral stricture, colostomy, or inability to urinate requiring chronic urinary catheter
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recruitment rate comparisons between physician referral and community advertisement | Completion of study (approximately 3.5 years) | — |
| Attrition rate in each arm | Completion of study (approximately 3.5 years) | * Evaluate percentage of finished duration of walking in each session and percentage of total finished session in the aerobic exercise arm. * Evaluate the percentage of attended sessions in the resistance training arm |
| Intervention effectiveness as measured by change in accelerometer measured physical activity | Completion of study (approximately 3.5 years) | — |
| Intervention effectiveness as measured by change in self-reported urinary/sexual function as measured by Expanded Prostate Cancer Index Composite (EPIC) | Completion of study (approximately 3.5 years) | -Intervention effectiveness will be compared between the three arms by comparing the change in self-reported urinary and sexual function. Mixed effects regression will be used to account for the longitudinal design. |
Outcome results
None listed