Overweight
Conditions
Keywords
Quinoa, Satiety, Visual analogue scale, Cross-over studies
Brief summary
The purpose of this study is to to assess the glycemic index and the satiating properties of different Quinoa varieties, using a Visual Analogue Scale in a sample of healthy overweight subjects.
Detailed description
Pilot study to evaluate the glycemic index, and the satiating effect using different Quinoa varieties in a group of healthy overweight subjects.
Interventions
DIETARY_SUPPLEMENTQuinoa variety 1
On the intervention day, the volunteers will consume the Quinoa Variety 1. Then during minutes 0, 15, 30, 45, 60, 90, 120, 180, 240 and 260 two types of methodologies were conducted: * In minutes 0, 15, 30, 45, 60, 90 and 120, blood samples were collected. * In minutes 0, 15, 30, 60, 90, 120, 180, 240 and 260, volunteers completed the Visual analogue scale questionnaire.
DIETARY_SUPPLEMENTQuinoa variety 2
On the intervention day, the volunteers will consume the Quinoa Variety 2. Then during minutes 0, 15, 30, 45, 60, 90, 120, 180, 240 and 260 two types of methodologies were conducted: * In minutes 0, 15, 30, 45, 60, 90 and 120, blood samples were collected. * In minutes 0, 15, 30, 60, 90, 120, 180, 240 and 260, volunteers completed the Visual analogue scale questionnaire.
DIETARY_SUPPLEMENTQuinoa variety 3
On the intervention day, the volunteers will consume the Quinoa Variety 3. Then during minutes 0, 15, 30, 45, 60, 90, 120, 180, 240 and 260 two types of methodologies were conducted: * In minutes 0, 15, 30, 45, 60, 90 and 120, blood samples were collected. * In minutes 0, 15, 30, 60, 90, 120, 180, 240 and 260, volunteers completed the Visual analogue scale questionnaire.
DIETARY_SUPPLEMENTQuinoa variety 4
On the intervention day, the volunteers will consume the Quinoa Variety 4. Then during minutes 0, 15, 30, 45, 60, 90, 120, 180, 240 and 260 two types of methodologies were conducted: * In minutes 0, 15, 30, 45, 60, 90 and 120, blood samples were collected. * In minutes 0, 15, 30, 60, 90, 120, 180, 240 and 260, volunteers completed the Visual analogue scale questionnaire.
DIETARY_SUPPLEMENTAnhydrous Glucose
On the intervention day, the volunteers will consume the control product. Then during minutes 0, 15, 30, 45, 60, 90, 120, 180, 240 and 260 two types of methodologies were conducted: * In minutes 0, 15, 30, 45, 60, 90 and 120, blood samples were collected. * In minutes 0, 15, 30, 60, 90, 120, 180, 240 and 260, volunteers completed the Visual analogue scale questionnaire.
Sponsors
Alicorp S.A.A.
Instituto de Investigación Hospital Universitario La Paz
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and women from 18 to 65 years old. * Body mass index (BMI) ≥25 and \<30 kg/m2. * Adequate cultural level and understanding for the clinical trial. * Signed informed consent
Exclusion criteria
* Individuals with BMI ≥30 or \<25 kg/m2 * Vegetarians or individuals with a fiber intake ≥30 g/day * Individuals diagnosed with Diabetes Mellitus * Individuals with dyslipidemia on pharmacological treatment * Individuals with hypertension on pharmacological treatment * Smokers or heavy drinking individuals (\>2-3 servings/day in men and \> 1 serving/day in women (1 serving=1 glass of wine or 1 bottle of beer)) * Individuals with large weight fluctuations or who have undergone in recent months a weight loss diet * Individuals with gastrointestinal diseases that affect the digestion or the absorption of nutrients * Individuals receiving at least the preceding 2 months a pharmacological treatment that modifies the lipid profile (for example, statins, fibrates, diuretics, corticosteroids, oral antidiabetic medications) * Pregnant or breastfeeding women * Women with menstrual irregularities (absence of menstrual cycle at least 2 months prior) * Individuals with intense physical activity
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycemic index | 0, 15, 30, 45, 60, 90, 120 min | The glycemic index is calculated with the incremental area under the curve of the glycemic response 7 time points ( 0 , 15 , 30, 45 , 60, 90 , 120 min) to 50 g intake carbohydrate food test food and reference |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| satiety hunger assessment (visual analogue scale) | just before taking the product, just after taking the product, 30, 60 , 90, 120, 180, 240 min and 260 min after taking the product) | visual analogue scale to assessment satiety and hunger will be picked up in 9 time points to calculate the area under the curve to get a score |
| Weight | day 1, 8, 15, 22, 29 | Weight |
| Adverse effects | day 1, 8, 15, 22, 29 | symptoms of gastrointestinal intolerance (nausea, diarrhea, bloating or other gastrointestinal disorder |
| Glucose metabolism related parameters | day 1, 8, 15, 22, 29 | glucose and insulin assessed in 7 point curves |
| height | day 1, 8, 15, 22, 29 | — |
| waist circumference | day 1, 8, 15, 22, 29 | — |
| BMI | day 1, 8, 15, 22, 29 | body mass index |
| Blood hormonal markers | just before taking the product, 15, 30, 45, 60, 90 and 120 min after consuming the product | ghrelin, GLP-1 (glucagon-like peptide) and peptide YY |
Countries
Spain
Outcome results
None listed