Observational Study of Preoperative Screen for Substance Abuse

Preoperative Screen for Substance Abuse in Trauma Patients Undergoing Emergency Operation: a Prospective Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02621411

Enrollment

1031

Registered

2015-12-03

Start date

2015-11-30

Completion date

2017-03-31

Last updated

2017-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative Screen for Substance Abuse in in Patients Undergoing Emergency Operation

Keywords

Substance abuse, Emergency operation, Preoperative screen

Brief summary

Substance abuse is a growing problem world wide, and treatment of substance abusers in the perioperative period, especially for emergency operation is challenging. The objectives of this study are to determine the proportions of substance abusers in the trauma patients undergoing emergency operation by preoperative screen, observe the differences of consumption of anesthetics and other medications during perioperative period between substance abusers and non-abusers, as well as postoperative complications, and explore an optimal scheme for substance abusers.

Interventions

DRUGSubstance use

Patients are found use of substances by preoperative screen

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients aged 16\ 70 years； * Informed consent signed

Exclusion criteria

* Aged\<16 years or \>70 years； * Refuse to sign consent; * Other conditions that may preclude the patients from the study, such as language barrier, psychiatric disorders, unable to attend research center for follow up. * Patients who enrolled to another research study or are taking experimental medication in last 3 months prior to this study. * Not suitable for the study, after assessment by the investigators.

Design outcomes

Primary

Measure	Time frame	Description
Proportion of substance abuser in all the emergency operation patients	1 year	The proportion will be calculated as the number of substance abusers / total number of enrolled calculated as the number of substance abusers / total number of enrolled patients

Secondary

Measure	Time frame	Description
Perioperative consumption of medications	1 day	Perioperative consumption of sulfentanil, midazolam, propofol, and muscle relaxant in substance abusers and non-abusers.
Incidence and severity of postoperative complications	30 days	—

Other

Measure	Time frame
Proportion of HIV, HCV, syphilis positive in substance abusers and non-abusers.	1 day

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026