Earlobe Creases Predict Prognosis in Chinese Patients With Acute Myocardial Infarction

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02618681

Acronym

ELC-CHN

Enrollment

902

Registered

2015-12-01

Start date

2015-06-30

Completion date

2019-06-30

Last updated

2015-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear Abnormalities, Prognosis

Keywords

earlobe crease, acute myocardial infarction

Brief summary

To investigate the feasibility of the earlobe crease as an early prognostic predictor for acute myocardial infarction(AMI) in Chinese population.

Detailed description

Primary Objective : 1 year primary composite end point (including the whole death, recurrent myocardial infarction, stroke, target vessel revascularization, stent thrombosis) in AMI patients with different types of earlobe crease. Secondary objective: 1. The incidence of complications during hospitalization 2. The rate of rehospitalization due to cardiovascular disease 3. The incidence of revascularization at 1 year after AMI

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Initial acute myocardial infarction(AMI) 2. Detection of a rise and/or fall of cardiac biomarker values (preferably cardiac troponin (cTn) with at least one value above the 99th percentile upper reference limit (URL)) and with at least one of the following: * Symptoms of ischemia * Development of pathologic Q waves in the electrocardiogram (ECG) * New or presumed new significant ST-segment-T wave (ST-T) changes or new left bundle branch block (LBBB). * Identification of an intracoronary thrombus by angiography or autopsy * Imaging evidence of new loss of viable myocardium or a new regional wall motion abnormality. 3. Type 1 (spontaneous myocardial infarction(MI)) in the third universal definition of MI: MI consequent to a pathologic process in the wall of the coronary artery (eg, plaque erosion/rupture, fissuring, or dissection), resulting in intraluminal thrombus. 4. Infarct related artery (IRA) showed that acute thrombus formation, IRA occlusion or stenosis ≥95%、≥90%～95%、≤90%，thrombolysis in myocardial infarction (TIMI)0-3 flow. 5. PCI(percutaneous coronary intervention)intervention（PCI for STEMI within 12 hours after symptom onset）. 6. Signed informed consent.

Exclusion criteria

1. Combined valvular heart disease, cardiomyopathy, blood diseases, skin diseases, rheumatic diseases, ischemic cerebrovascular disease, tumor, etc. 2. Previous myocardial infarction. 3. Previous PCI and coronary artery bypass graft(CABG). 4. Chronic total occlusion(CTO)lesions. 5. Ear malformation. 6. Ocular diseases. 7. Participating in a clinical study.

Design outcomes

Primary

Measure	Time frame
primary composite end point (including the whole death, recurrent myocardial infarction, stroke, target vessel revascularization, stent thrombosis) in AMI patients with different types of earlobe crease.	1 year

Countries

China

Contacts

Primary ContactJing Qi, Master

saraok@126.com

Outcome results