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Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection

Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection of Living Donor.

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02617498
Acronym
LDLT
Enrollment
80
Registered
2015-12-01
Start date
2013-04-30
Completion date
2015-11-30
Last updated
2016-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Liver Disease

Keywords

living donor liver transplantation

Brief summary

Consecutive patients, who were treated for end stage liver cirrhosis by LDLT were included in this a prospective study.Patients enrolled in the study divided into two groups according to the day of surgery. The study population was divided into two groups; group (A) Parenchymal liver transection was performed by harmonic scalpel (HS) and group (B) Parenchymal liver transection was performed by spray diathermy (SD).

Detailed description

Consecutive patients, who were treated for end stage liver cirrhosis by LDLT were included in this a prospective study.Patients enrolled in the study divided into two groups according to the day of surgery. The study population was divided into two groups; group (A) Parenchymal liver transection was performed by harmonic scalpel (HS) and group (B) Parenchymal liver transection was performed by spray diathermy (SD). Donors and recipient were followed up after hospital discharge with laboratory investigation, abdominal ultrasound, MRCP in selected cases every month for the first month, then every 6 months and then every year postoperatively. Follow up visits included clinical examination, laboratory investigation, doses of immunosuppressive, radiological examination, and doppler US. The primary outcome was the amount of blood loss during transection. Secondary outcomes were operative time, time of transection, speed of transection/minutes , number of ligation used, degree of postoperative injury which assessed by daily liver function, WBC, C reactive protein, pathological changes at the cut surface, postoperative morbidity (including biliary leakage, collection), cost and hospital stay.

Interventions

parenchymal liver transection was performed either by harmonic scalpel after demarcation of line of transection by intraoperative US and doppler.

DEVICEspray mode diathermy

parenchymal liver transection was performed either by spray mode diathermy after demarcation of line of transection by intraoperative US and doppler.

Sponsors

Mansoura University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
10 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Consecutive patients, who were treated for end stage liver cirrhosis by LDLT

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
the amount of blood loss6 hours during operationthe amount of blood loss

Secondary

MeasureTime frame
operative timeminutes during operations
number of ligation used,hours during operations
extent of necrosis at the cut surfaceone week postoperative

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026