Menorrhagia
Conditions
Brief summary
To compare the efficacy of tranexamic acid and diosmin in reducing menstrual blood loss in women having Intra Uterine Contraceptive Device (IUD) and suffer from menorrhagia.
Interventions
DRUGTranexamic Acid
use tranexamic acid oral tablets 500 mg two tablets every six hour with the onset of the first day of menstrual cycle till the end of bleeding then The amount of menstrual flow will be calculated by the PBAC
DRUGDiosmin
use diosmin oral tablets 500 mg t.d.s (three times daily) with the onset of the first day of menstrual cycle till the end of bleeding.then The amount of menstrual flow will be calculated by the PBAC
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Women complaining from an menorrhagia secondary to a current copper IUD use. * Age: 20-40years. * Menorrhagia , will be defined as a PBAC-Score greater than 100. * No systemic causes of abnormal uterine bleeding as hypertension and hemorrhagic blood diseases. * No other local causes of abnormal uterine bleeding as, (fibroid, adenomyosis, polyps). * No drugs decreasing blood coagulation. * Well fitted IUD not misplaced.
Exclusion criteria
* Age \<20y and \>40y. * Irregular menstrual cycle. * Presence of systemic causes of abnormal uterine bleeding as hypertension and hemorrhagic blood diseases. * Presence of other local causes of abnormal uterine bleeding as, (fibroid, adenomyosis, polyps). * Taking drugs decrease blood coagulation. * Misplaced IUD.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The amount of reducing heavy menstrual flow will be calculated by the PBAC. | the first 24hours | measure the bleeding rate will be by the pictorial blood assessment chart (PBAC). |
Countries
Egypt
Contacts
Primary Contactahmed alanwar, MD
Outcome results
None listed