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Surgery for Mesothelioma After Radiation Therapy SMART for Resectable Malignant Pleural Mesothelioma

Surgery for Mesothelioma After Radiation Therapy SMART for Resectable Malignant Pleural Mesothelioma

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02613299
Enrollment
5
Registered
2015-11-24
Start date
2016-06-14
Completion date
2025-05-29
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mesothelioma, Solitary Fibrous Tumor of the Pleura

Brief summary

The purpose of this study is to determine whether radiation therapy decreases tumor size and tumor spread. The investigators will consent subjects that have been diagnosed with mesothelioma and will undergo radiation therapy followed by surgical resection as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.

Interventions

None listed

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Subject provides informed consent * Subject is \>18 years of age * Subject is deemed competent for making medical decisions * Subject is scheduled to undergo radiation followed by extrapleural pneumonectomy. * Subject is a surgical candidate * A negative pregnancy test is required in women of child-bearing potential, as standard of care.

Exclusion criteria

* Subject is \<18 years old.

Design outcomes

Primary

MeasureTime frame
Survival status upon review of patient records annuallyUp to 10 years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026