Clinical Evaluation of Leech Therapy in the Treatment of Knee Osteoarthritis

Randomized Controlled Clinical Evaluation of Leech Therapy in the Treatment of Knee Osteoarthritis

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02612974

Acronym

Leech Therapy

Enrollment

Registered

2015-11-24

Start date

2010-01-31

Completion date

2012-06-30

Last updated

2015-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Qurse mafasil, leech therapy, Hirudinaria granulosa

Brief summary

This study has been designed to conduct as Randomized comparative clinical study.

Detailed description

Two groups, group B received Qurse Mafasil tablet orally two tablets two times daily for 8 weeks while group A received Leech therapy once weekly for 8 weeks along with Qurse mafasil.

Interventions

BIOLOGICALHirudinaria granulosa, qurse mafasil

compare the efficacy of both groups

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* knee osteoarthritis

Exclusion criteria

* pregnancy, * lactation, * anaemia

Design outcomes

Primary

Measure	Time frame
KOOS Score	end of 6 weeks
VAS	end of 6 weeks
Active Range of Motion	end of 6 weeks
Knee circumference	end of 6 weeks
15 m walking time test	end of 6 weeks

Secondary

Measure	Time frame
KOOS subscores	end of 6 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026