Cryoprobe Transbronchial Lung Biospy in Patients With Mechanical Ventilation

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02611297

Enrollment

Registered

2015-11-20

Start date

2013-11-30

Completion date

2015-12-31

Last updated

2015-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial Disease, Lung Diseases

Keywords

Cryoprobes, Cryobiopsy, Transbronchial lung biopsy

Brief summary

The purpose of this study is to evaluate the the diagnostic yield and safety of transbronchial lung biopsies (TBLB) with cryoprobe in patients with mechanical ventilation.

Interventions

PROCEDURECryoprobe

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* ≥18 years old * Patients with mechanical ventilation. * Patients with diffuse lung disease of unknown etiology. * Need for confirming/excluding a diagnosis, with therapeutical and prognosis implications. * Inform consent signed by family.

Exclusion criteria

* Use of anticoagulant therapy or presence of a coagulation disorder (abnormal platelets counts, international normalized ratio \> 1.5). * Comorbidities that could increase the risk of the TBLB. * Bullous emphysema. * Hemoptysis, pneumothorax. * Severe respiratory insufficiency requiring PEEP \>12 cm H2O

Design outcomes

Primary

Measure	Time frame
Adverse events related to transbronchial lung biopsy (TBLB) with cryoprobe	27 months

Secondary

Measure	Time frame
Diagnostic yield of transbronchial lung biopsy (TBLB) obtained by cryoprobes	27 months

Countries

Spain

Contacts

Primary ContactVirginia Pajares, MD, PhD

vpajares@santpau.cat+34935565972

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026