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Functional Significance of Complexity Measures in the Sensory-motor Behavior

Functional Significance of Complexity Measures in the Sensory-motor Behavior: Are There Potential Clinical Applications?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02610647
Acronym
NEURO COMP
Enrollment
60
Registered
2015-11-20
Start date
2017-06-06
Completion date
2017-08-31
Last updated
2025-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Brief summary

The main objective of this study is to compare between groups the level of complexity of the estimated sensorimotor performance through multi-fractal (minmaxMF-DFA) exponents.

Detailed description

The secondary objectives of this study are to compare the level of complexity of the estimated sensorimotor performance using the(A) mono-fractal exhibitors (the αDFA values) and the (B) coefficient of variation (CV) between groups.

Interventions

OTHERAnti-noise helmet

Patients will don a helmet that prevents them from hearing during the tapping test.

OTHERBlinding mask

Patients will don a mask that prevents them from seeing during the tapping test.

DRUGWrist anesthesia

Prior to the tapping test, regional anesthesia is performed in the form of sensory blocks distal to the wrist: injection of ropivacaine 7.5mg / ml is carried out successively in contact with three nerves (ulnar, median and radial) with a volume of 2 ml for nerve, for a total of 45mg.

Subjects will be placed at a table in a sitting position where they will perform a rhythmic finger tapping test. The seat height is adjusted so that the front dominant arm rests comfortably on the table. Subjects will be equipped with headphones to receive auditory signals during a first synchronized phase of tapping. After the last auditory signal, participants will continue the tapping task by themselves as directed: after the metronome stops,continue tapping the prescribed tempo as accurately and consistently as possible throughout the test. The movements of the index finger will be measured by a single-axis accelerometer (15 × 15 mm) attached to the nail.

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The subject does not practice music intensively (\<1h / day on average)

Exclusion criteria

* The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, or under guardianship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant, parturient, or breastfeeding * The subject regularly practices music * The subject is suffering from a neurodegenerative disease of the central or peripheral nervous system which may affect the sensorimotor control of rhythmic movements of the upper limb * The subject has had a recent trauma of the upper limb * The subject is suffering from uncorrected visual and hearing impairment

Design outcomes

Primary

MeasureTime frameDescription
minmaxMF-DFA value during the tapping testDay 0The level of complexity of the estimated sensorimotor performance as measured by the multi-fractal exponents.

Secondary

MeasureTime frameDescription
Coefficient of variationDay 0
αDFA value during the tapping testDay 0The level of complexity of the estimated sensorimotor performance as measured by the single-fractal exponent.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026