Rib Fractures
Conditions
Keywords
Multiple Rib Fractures, Frail Chest
Brief summary
An observational study to derive clinically relevant and predictive rib fracture classification systems, based on retrospective and prospective cohorts, incorporating assessment of PROMs (Patient Reported Outcome Measures) and healthcare utilisation
Detailed description
The aim of this study is to derive radiology-based classifications of rib fractures and to test whether such classifications have a value in the prediction of clinical outcomes and patient reported outcome measures. The first aspect of work is to analyse existing radiology investigations (plain chest radiography (CXR) and derive classifications of rib fractures that, in the retrospective cohort of operated and non-operated cases, could have potential value in the guidance of management and prediction of clinical outcomes. The second aspect will be to evaluate the feasibility of collection of Patient Reported Outcome Measures in patients suffering multiple rib fractures, which will be used to assess the impact of the radiological classifications. The indications for surgery will remain according to current clinical practice and the management algorithms that have been developed previously in the department.
Interventions
OTHERrib fracture fixation
Use of MatrixRib, where indicated, according to departmental protocol
Sponsors
University of Sheffield
Sheffield Teaching Hospitals NHS Foundation Trust
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Multiple simple rib fractures * Flail chest
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Acute Pain | up to 2 years | Visual Analogue Score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Forced Vital Capacity (FVC) | up to 2 years | — |
| Length of critical care unit stay | up to 1 year | — |
| Complications during critical care unit stay | up to 1 year | adverse events as assessed by CTCAE v4.0 |
| Length of hospital stay | up to 1 year | — |
| Complications during hospital stay | up to 1 year | adverse events as assessed by CTCAE v4.0 |
| Forced Expired Volume in 1 second (FEV1) | up to 2 years | — |
| Quality of Life - EQ5D | up to 2 years | EuroQol Group EQ5D |
| Quality of Life - EORTC (European Organisation for the Research and Treatment of Cancer) QLQ-C30 (Quality of Life Questionnaire - Cancer-30) | up to 2 years | EORTC QLQ-C30 |
| Quality of Life - EORTC QLQ-LC13 (Lung Cancer13) | up to 2 years | EORTC QLQ-LC13 |
| Healthcare cost | up to 2 years | procedural costs plus hospital cost plus community healthcare costs |
| Quality of Life - SF36 (Short Form 36) | up to 2 years | SF-36 |
Countries
United Kingdom
Outcome results
None listed