Non-responders to Antiplatelet Treatment in Acute Ischaemic Stroke)

NATIS: Non-responders to Antiplatelet Treatment in Acute Ischaemic Stroke

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02607358

Acronym

NATIS

Enrollment

496

Registered

2015-11-18

Start date

2015-01-31

Completion date

2016-08-31

Last updated

2016-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Ischemic Stroke

Keywords

Clopidogrel, acetacylic acid, antiplatelet therapy, HOTPR, VerifyNow

Brief summary

Determination of frequency of Clopidigrel- and Acetacylicacid-non-responders (HOTPR) in acute ischemic stroke patients.

Detailed description

Determination of frequency of Clopidigrel- and Acetacylicacid-non-responders (HOTPR) in acute ischemic stroke patients using the VerifyNow system.

Interventions

OTHERblood sampling for HOTPR-testing

All subjects are tested for responderstatus using the VerifyNow System

Study design

Observational model

COHORT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Suspected acute ischemic stroke and loading dose of Clopidogrel or Acetacylicacid

Exclusion criteria

* Previous treatment with platelet inhibitor * NOAC or Vitamin K-antagonist treatment * Final diagnosis other than Ischemoc stroke or Transitoric ischemic attack

Design outcomes

Primary

Measure	Time frame	Description
Responder status	immediately	Platelet reactivity with PRU measurement

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026