Cervical Cancer, Cervical Intraepithelial Neoplasia
Conditions
Keywords
DNA methylation, Cervical cancer
Brief summary
The purpose of this prospective study is to evaluate whether DNA methylation can be applied in cervical cancer screening.
Interventions
None listed
Sponsors
Mackay Memorial Hospital
Li Shin Hospital
Chang Gung Memorial Hospital
iStat Biomedical CO., Ltd.
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* women with age ≥20 and sexual experience * Agree to sign ICF
Exclusion criteria
* women had received Hysterectomy * women had destructive therapy for cervical lesions in 6 months, for examples: conization, Laser or cryotherapy, chemotherapy, and radiation therapy * Women are at pregnancy or had baby delivery in 6 weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Performance of DNA methylation in identification of CIN3 or worse. | 3 years | Patient's information, including clinical diagnosis and the molecular testing results etc., will be collected. Performances of the screening tools will be compared. |
Countries
Taiwan
Contacts
Primary ContactChien-Ping Hung
Backup ContactHsiu-yuan Tsao
Outcome results
None listed