Late Premature Infants, Systemic Nutritional Management
Conditions
Keywords
late preterm infants, nutrition, systemic management
Brief summary
The purpose of the project is to investigate the status of nutrition management of late preterm infants in the member hospitals in the Beijing association of preterm infants, and set up the systemic nutritional management of late preterm infants, Including parenteral nutrition and enteral feeding. And to compare the differences of growth and complications of these infants between groupings applicationg and not applicating the systemic nutritional management of late preterm infants,and to validate its feasibility and validity.
Detailed description
The research content of the project includes three parts: 1. Investigation on nutritional status of late preterm infants. 2. Setting up systemic nutritional management of late preterm infants 3. Comparing nutritional and growth status of the late preterm, short-term and long-term complications between the groups applicating and not applicating the systemic nutritional management of late pretern infants.
Interventions
PROCEDUREnew systemic nutrition management protocol
a new established systemic nutrition management protocol
Sponsors
Peking University First Hospital
Peking University People's Hospital
Peking University Third Hospital
Beijing Children's Hospital
Capital Institute of Pediatrics, China
Beijing Obstetrics and Gynecology Hospital
Beijing Huaxin Hospital
Beijing Friendship Hospital
Beijing Ditan Hospital
Bayi Children's Hospital Affiliated to Beijing Military Gen Hospital
Beijing Shangdi Hospital
Beijing Tongzhou District Maternal and Child Health Hospital
Beijing Yanqing County Hospital
People's Hospital of Beijing Daxing District
Beijing Hospital
Civil Aviation General Hospital
Beijing Anzhen Hospital
Military 301 Hospital
Beijing Haidian Maternal and Child Health Hospital
Beijing 302 Hospital
Beijing Chaoyang District Maternal and Child Health Hospital
China-Japan Friendship Hospital
Military 306 Hospital
Beijing Chao Yang Hospital
Navy General Hospital, Beijing
Peking Union Medical College Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* preterm infants with gestational age 34 weeks to 36 weeks and 6 days
Exclusion criteria
* preterm infants with gestational age\<34 weeks or \>36 weeks and 6 days * abnormality of digestive system * genetic and metablic disease * severe congenital heart disease( with hemodynamic changes that influencing enteral feeding)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| days of postnatal life when enteral nutrition reaching 120kcal/kg/d | 29 months |
| weight gain(g/kg/week) | 29 months |
| length gain(cm/week) | 29 months |
| circumference gain(cm/week) | 29 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| days of postnatal life with the lowst weight during hospitalisation(d) | 29 months | — |
| the lowest weight during hospitalisation(g) | 29 months | — |
| days of postnatal life that regain birth weight(d) | 29 months | — |
| incidence of neonatal infection(%) | 29 months | — |
| incidence of hypoglycemia(%) | 29 months | — |
| incidence of hypebilirubinemia(%) | 29 months | — |
| incidence of hyperglycemia(%) | 29 months | — |
| incidence of neonatal anemia(%) | 29 months | — |
| days of postnatal life when reaching full enteral nutrion(d) | 29 months | the incidence of complications of preterm infants |
| proportion of breast milk feeding(%) | 29 months | — |
Outcome results
None listed