Preoperative Fasting
Conditions
Brief summary
Fasting (according to ASA, ESA or institutional guidelines) is an important strategy to minimize the risk of regurgitation, vomiting and pulmonary aspiration during general anaesthesia; the effect of fasting time for clear fluid on gastric pH in children is goal of this study and can be investigated in children undergoing elective procedures in general anaesthesia and intubation without inconvenience or additional invasive procedure and hence without additional risk Hypotheses: Gastric pH is higher in children that drink clear fluids until premedication before anaesthesia induction than in those that drink until 2 hours before anaesthesia induction
Interventions
PROCEDUREclear fluid ingestion
drinking of clear fluid in preoperative period
Sponsors
University Children's Hospital, Zurich
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
1 Years to 15 Years
Healthy volunteers
Yes
Inclusion criteria
age \> 1 / \< 16 years ASA class l or ll elective surgery requiring general anaesthesia using tracheal intubation
Exclusion criteria
disease or dysfunction of gastrointestinal tract chronic diseases or conditions not compatible with ASA class l or ll
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| gastric pH | within 10 min after tracheal intubation | gastric pH is measured from gastric contents which is sampled in a syringe via an orogastric tube immediately during anaesthesia after tracheal intubation induction; suctioning of the stomach after intubation is a procedure routinely performed in every intubation child in our institution |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| subjective feeling of hunger/thirst | baseline | subjective feeling of hunger/thirst given as yes or no answer |
| Postoperative Nausea and Vomiting (PONV) in recovery unit | recovery period, on the average within 90 minutes after end of anaesthesia | — |
| Behaviour during recovery period | recovery period, on the average within 90 minutes after end of anaesthesia | Rating Scale1-5 by blinded nurse (5: severely agitated/emergence delir with subsequent drug therapy, 4: agitated/emergence delir; 3: slightly agitated; 2: complaining pain but cooperative; 1: cooperative) |
| gastric aspirate volume | within 10 min after tracheal intubation | gastric aspirate volume is the amount of gastric contents which is sampled in a syringe via an orogastric tube immediately during anaesthesia after tracheal intubation induction; suctioning of the stomach after intubation is a procedure routinely performed in every intubation child in our institution |
| Nurse's Impression of patient's satisfactory | baseline | subjective feeling of the Nurse regarding patient's satisfactory given as rating scale from 1 to 4 |
| blood Ketone measurement | intraoperative | measurement of blood Ketone with a portable poc Ketone measurement device |
| Behaviour during anaesthesia induction | on the average within 20 minutes after arrival of patient in operating theatre | Rating scale1-5 by (blinded) anaesthetist: 1: cooperating - 2: anxious but cooperating - 3: hostile - 4: crying - 5: agitated/fighting |
Countries
Switzerland
Outcome results
None listed