Depression
Conditions
Brief summary
Depression treatments including physical activity and sleep management has been shown to relieve depressive symptoms among participants suffering depressive episodes. This study evaluates the potential of these methods as prevention of depressive relapse or recurrence
Interventions
BEHAVIORALTherapist-assisted iCBT
13 week long individualized prevention program containing, physical activation, sleep management, tailored cognitive behavioral therapy for individual problems.
BEHAVIORALMonthly screening with feedback
Participants are screened with a depression inventory each month and receives feedback from a therapist on the results
Sponsors
Lund University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* A history of at least one episode of Major Depression. * If medicating - Taking a stable (since one month) and therapeutic dosage of antidepressant medication * Being able to read and write Swedish * Having access to the internet
Exclusion criteria
* Fulfilling the criteria for Major depression * Bipolar disorder * Psychosis * Substance abuse * Suicidality * Currently in psychotherapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Depressive relapse (change in diagnostic status, SCID-I) | Baseline - 12 months | Monthly screening via Montgomery-Asberg Depression Rating Scale - Self rated & Structured Clinical Interview for DSM IV |
| Change from baseline in depressive symptoms (MADRS-S) | Baseline - 6 months | Change in depressive symptoms will be measured by an internetbased version of the Montgomery-Asberg Depression Rating Scale - Self rated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in Outcomes Questionnaire 45 (OQ-45) | Baseline - 3 months | The OQ-45 measures functioning in 3 domains: Symptom distress (heavily loaded for depression and anxiety), Interpersonal functioning, and Social Role. It enables the clinician to assess functional level and change over time. |
| Self reported treatment seeking | Baseline - 12 months | Treatment seeking among participants is recorded as secondary outcome variable |
| Change from baseline in the International Physical Activity Questionnaire (IPAQ) | Baseline - 3 months | The International Physical Activity Questionnaire is a measure of physical activity |
| Change from baseline in health related quality of life (EQ-5D) | Baseline - 3 months | Health related quality of life will be measured by an internet based version of the EQ-5D. |
| Insomnia Severity Index (ISI) | Baseline - 3 months | Insomnia issues |
| Alcohol Use Disorder Identification Test (AUDIT) | Baseline - 3 months | — |
| Morisky Medication Adherence Scale (MMAS-8) | Baseline - 3 months | Self-reported measure of medication adherence |
| Time to depressive relapse | Baseline - 12 months | Time to depressive relapse is recorded as secondary outcome variable |
Countries
Sweden
Outcome results
None listed