A Comparison of Colonic Bile Acid Content Following Right and Left Colectomies

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02596516

Enrollment

100

Registered

2015-11-04

Start date

2015-12-31

Completion date

2020-12-31

Last updated

2015-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bile Acid and Salts, Colectomy

Brief summary

The aim of this study is to evaluate whether there is a difference in the bile acid content in the bowel in patients after right versus left colectomy. There is compelling evidence that patients under going resection of the right colon versus left coolon have a lower polyp detection rate in surveillance colonoscopies. The investigators intend to evaluate feces of patients undergoing left and right colectomies; prior to their surgery and again three and six months aftet the surgery. The investigators plan to compare the content of the different bile acids and to compare the content between the two groups.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age above 18. * Patients intended to undergo a colectomy for colonic cancer * Patients willing and participate and able to sign an informed consent

Exclusion criteria

* Age under 18. * Patients with Inflammatory Bowel Disease (Crohn's, Ulcerative colitis). * Patients refusing to participate or are unable to understand or sign an informed consent

Design outcomes

Primary

Measure	Time frame
Colonic bile acid content	two years

Outcome results