Acute Heart Failure
Conditions
Keywords
Registry, Heart failure, Hospitalized, Global, Morbidity, Mortality, Quality of life, AHF
Brief summary
The clinical characteristics, initial presentation, management, and outcomes of patients hospitalized with new-onset (first diagnosis) heart failure (HF) or decompensation of chronic HF are poorly understood worldwide. REPORT-HF is a global, prospective, and observational HF disease registry designed to characterize patient trajectories longitudinally during and following an index hospitalization for acute HF.
Interventions
None listed
Sponsors
Novartis Pharmaceuticals
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients at least 18 years old, or older for those countries where the adult age is above 18 years of age, hospitalized with a primary diagnosis of acute heart failure.
Exclusion criteria
1-Concomitant participation in any/a clinical trial with any investigational treatment (for any sponsor). 2\. Use of investigational drugs within 5 half-lives of enrollment, or until the expected pharmacodynamic effect has returned to baseline, whichever is longer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healthcare Resource Utilization assessed by number of patients with re-hospitalizations | up to 3 years |
| Percentage of patients who die during the follow-up period post-discharge | up to 3 years |
| Percentage of patients who are re-hospitalized by primary re-hospitalization reason (Cardiovascular and non-Cardiovascular) | up to 3 years |
| Number of patients with different characteristics of post-discharge patient management | up to 3 years |
| Number of patients with different characteristics of heart faliure (HF) at hospitalization | From admission to discharge of the patient's index hospitalization (minimum 24 hours) |
| Percentage of patients who die during the index hospitalization | From admission to discharge of the patient's index hospitalization (minimum 24 hours) |
Secondary
| Measure | Time frame |
|---|---|
| Caregiver burden based on Caregiver Burden Questionnaire -Heart Failure (CBQ-HF) and Work Productivity and Activity Impairment (WPAI) questionnaires | up to 3 years |
| Correlation ratio between practice patterns and outcomes | up to 3 years |
| Health-related Quality of life (HRQoL) based on patient reported data as measured by EQ-5D and the Kansas City Cardiomyopathy Questionnaire (KCCQ) questionnaires | up to 3 years |
Countries
Algeria, Argentina, Australia, Austria, Brazil, Bulgaria, Canada, Chile, China, Colombia, Ecuador, Egypt, Germany, Greece, Guatemala, India, Indonesia, Israel, Japan, Jordan, Lebanon, Malaysia, Mexico, Morocco, Netherlands, Norway, Panama, Philippines, Romania, Russia, Saudi Arabia, South Africa, South Korea, Spain, Sweden, Switzerland, Taiwan, Thailand, Tunisia, Turkey (Türkiye), United Arab Emirates, United Kingdom, United States, Vietnam
Outcome results
None listed