Breath Analysis in Healthy Controls

Exhaled Breath Analysis by Secondary Electrospray Ionization (SESI-MS) in Healthy Controls

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02595632

Enrollment

183

Registered

2015-11-03

Start date

2015-11-30

Completion date

2020-08-31

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exhaled Breath, Healthy Subjects, Mass Spectrometry

Brief summary

The purpose of this study is to detect a specific profile of breath in healthy subjects by an untargeted metabolomic study using exhaled breath analysis by mass spectrometry.

Interventions

OTHERNo intervention

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

1. Normal spirometry (forced expiratory volume in 1 second (FEV1) \> 80%, forced vital capacity (FVC) \> 80%, FEV1/FVC \> 70%.). 2. Age between 18 and 90 years at study entry.

Exclusion criteria

1. Presence of an active malignancy. 2. Presence of any lung disease (e.g. asthma, chronic obstructive pulmonary disease (COPD), sarcoidosis) 3. Acute inflammatory disease (e.g. common cold) within the last 6 weeks. 4. Acute or chronic hepatic disease. 5. Renal failure or renal replacement therapy.

Design outcomes

Primary

Measure	Time frame
The primary outcome will be the mass spectrometric exhaled breath pattern of healthy subjects.	1 day, single measurement, no follow up

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026