Metabolism and Oxygen Consumption During Functional Electrical Stimulation Cycling in COPD

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02594722

Enrollment

Registered

2015-11-03

Start date

2016-04-30

Completion date

2017-04-30

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

COPD, Functional Electrical Stimulation Cycling, Pulmonary Rehabilitation

Brief summary

Chronic Obstructive Pulmonary Disease (COPD) had systemic repercussion and lead to peripheral muscular dysfunction. Muscular atrophy limits aerobic capacity and is a major limitation of daily activity and quality of life. Technologies likes' neuromuscular electrical stimulation (NMES) are currently being adapted and tested to support exercise training. The investigators hypothesized that functional electrical stimulation cycling improves VO2 and aerobic capacities during exercise compared to endurance training.

Interventions

DEVICEFES-cycling

Patients performed an endurance tests with functional electrical stimulation during 30 minutes with an oxygen uptake measure.

DEVICEClassic cycloergometer

Patients performed an endurance tests on classic ergometer during 30 minutes with a sham electrical stimulation with an oxygen uptake measure.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* COPD (Stade II, III or IV) * Inform consent

Exclusion criteria

* Pulmonary rehabilitation contraindication * Patient with Pacemaker * Patient in acute exacerbation * Patient with neurologic comorbidity * Anemiae

Design outcomes

Primary

Measure	Time frame
oxygen uptake (VO2)	during 30 minutes exercise

Secondary

Measure	Time frame	Description
Ratio Ventilation/VO2 (Ventilation equivalent for oxygen)	during 30 minutes exercise	Number of liters of air must be ventilated to consume 1 liter of O2
Ratio Ventilation/VCO2 (Ventilation equivalent for carbon dioxide)	during 30 minutes exercise	Number of liters of air must be ventilated to reject 1 liter of CO2
cardiac output	during 30 minutes exercise	—
Muscular fatigue	after 30 minutes exercise	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026