Sleep Apnea Syndrome
Conditions
Brief summary
This is a prospective, interventional cohort study of drug-induced sleep endoscopy (DISE). The goal is to evaluate the upper airway in a cohort of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) diagnosed in a prior polysomnography. This study correlates the sedation level measured by entropy during DISE using propofol via a TCI pump with the local obstruction patterns of the upper airway according to the VOTE classification. As OSAHS is a widespread disease and the DISE procedure has become a common tool for diagnosis and evaluation of further treatment, a growing number of research articles deal with this topic. These articles are available through pubmed.
Interventions
PROCEDUREDrug induced sleep endoscopy
Titration of propofol using a target controlled Infusion pump and description of the upper airway according to the VOTE classification
Sponsors
Technical University of Munich
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* documented sleep apnea Syndrome with an AHI \> 5 diagnosed by polysomnography
Exclusion criteria
* active infection * performed oral, head or neck surgery, pregnancy, * ASA classification III or higher, * chronic use of alcohol, sedatives or illicit drugs and chronic * obstructive pulmonary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| collapse of the upper airway according to the VOTE classification | 30 minutes |
Countries
Germany
Outcome results
None listed