Effects of the Low-level Laser Therapy (LLLT) on Muscle Strength (MS) of the Patients With Kidneys Failure (KF)

Effects of the Different Intensities of the Low-level Laser Therapy on Handgrip Test on Patients With Kidneys Failure: A Randomized, Controlled Clinical Trail

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02586376

Acronym

LLLTMSKF

Enrollment

Registered

2015-10-26

Start date

2015-10-31

Completion date

2016-02-29

Last updated

2016-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Failure

Brief summary

The low-level laser therapy (LLLT) has been used in many inflammatory disorders. More recently the LLLT was associated with an improvement in the muscle strength and endurance. But, these effects were described only in health or athletic individuals. In this randomized and controlled clinical trails, the investigators will study the effects of LLLT on muscle strength of the patients with kidneys failure on long time hemodialysis treatment. Additionally, investigators will explore three different intensities up the muscle strength.

Detailed description

This study will be conducing in a large hospital that is reference in kidneys disorders treatments. 16 patients will be randomized for placebo, 4J, 6J, or 8J low-level laser therapy (LLLT). The maximal voluntary contraction (MVC) will be test by handgrip test before and after de LLLT. One-week interval between the LLLT will gave to reduce the influence between the treatments. Moreover the endurance test will be use to evaluate the muscle oxidation impact of the LLLT.

Interventions

DEVICE0J LLLT

Sham Low-Level Laser Therapy (Sham LLLT): perform with the machine off.

DEVICE4J LLLT

4J Low-Level Laser Therapy (4J LLLT) irradiation will be perform with 4J.

DEVICE6J LLLT

6J Low-Level Laser Therapy (6J LLLT) irradiation will be perform with 6J.

DEVICE8J LLLT

8J Low-Level Laser Therapy (8J LLLT) irradiation will be perform with 8J.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

30 Years to 60 Years

Healthy volunteers

Inclusion criteria

* chronic kidney failure, * long time hemodialysis treatment (\>18 months)

Exclusion criteria

* any health disturbance that can reduces the handgrip test performance beyond to the produced by the chronic kidney failure.

Design outcomes

Primary

Measure	Time frame
Muscle Strength (Handgrip Test)	once a week throughout 4 weeks

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026