Iodine Nutrition During Pregnancy and Related Neonatal Physical Development

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02586220

Enrollment

250

Registered

2015-10-26

Start date

2015-08-31

Completion date

2016-07-31

Last updated

2020-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iodine Deficiency, Pregnancy

Brief summary

Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status.Our overall aim is to monitor iodine status of pregnant women in China, and to examine the correlation between maternal urine iodine concentration (UIC) and newborn physical development level.

Detailed description

Background: Recent studies have found, in both developed and developing countries, there is still a considerable number of pregnant women in iodine deficiency status. Our overall aim is to monitor iodine status of pregnant women in China, and to examine the correlation between maternal urine iodine concentration (UIC) and newborn physical development level. Design: prospective cohort study Methods: During August - December 2015,250 participants(28-32 weeks' gestation) were selected to participate in the study.The investigators collect the spot urine samples(n=750) once every two weeks. Setting: Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine. Participants: 150 normal pregnant women and 100 pregnant women with gestational diabetes (28-32 weeks' gestation) and their newborns were selected to participate the study.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

22 Years to 35 Years

Healthy volunteers

Inclusion criteria

* 22-35 years, * 28-32 weeks' gestation,

Exclusion criteria

* a known history of thyroid disease in the non-pregnant state and previous.

Design outcomes

Primary

Measure	Time frame
urinary iodine (UI) concentrations	up to three months

Secondary

Measure	Time frame	Description
thyroid stimulating hormone level of newborns	up to three months	—
daily iodine intake of pregnant women	up to three months	Daily iodine intake was estimated using the total diet study approach

Countries

China

Outcome results