Infertility
Conditions
Brief summary
Study Goals: 1. Finding the prevalence of bacteria of the sperm in an innovative and more accurate methode 2. Understanding the effect of microbes on the process of capacitation 3. The impact of microbes in the sperm on IVF success rate 4. Finding the incidence of vaginal bacteria and their relationship to bacteria of the sperm 5. The impact of vaginal flora on IVF success rate
Detailed description
Prospective non interventional study in the Department of Life Sciences, Bar-Ilan University and IVF Unit at Meir Hospital. The control group consisting of 50 semen samples from men with no sperm problems and 50 vaginal samples from their partners. The study group consisting of 50 semen samples from men with male fertility problems and 50 vaginal samples from their partners. The semen taken from the remains after fertilization of the IVF laboratory. (Liquid otherwise routinely thrown). Vaginal samples taken from women undergoing IVF treatment under anesthesia after informed consent. Enrollment also collect the following data: age, race, chronic illnesses, past surgeries and former fertility treatments. Data will be collected through anamnesis of the patient or the medical file after consent.
Interventions
OTHERno intervention
Sponsors
Meir Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Male and female undergoing fertility treatments
Exclusion criteria
* Male and female not undergoing fertility treatments
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The percent of successful IFV treatments | 24 months | Using 16-S Ribosomal RNA analysis to quantify and compare (type and percentages) of bacterial components in sperm samples from fertile and infertile men and their impact on IVF treatments success rate |
Outcome results
None listed