Chronic Periodontitis (CP) Subjects.
Conditions
Brief summary
Aim: To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects. Materials and methods: The study is non surgical interventional trial, includes 50 CP subjects in the age group of 35- 60 years selected from the OPD (Out Patient Department) of department of periodontology Tatyasaheb Kore Dental College and Research center (TKDC and RC), Kolhapur. CP subjects were equally divided into test group and control group. Liver function test- aspartate aminotransferase (AST), alanine aminotransferase (ALT) were checked at baseline and at 1 month after treatment. Clinical examination includes plaque index, gingival index, sulcus bleeding index, probing depth, clinical attachment loss.
Interventions
PROCEDUREScaling and root planing
scaling and root planing as an intervention was done in patients of the test group
Sponsors
Tatyasaheb Kore Dental College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
35 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
1. Subjects with CP (moderate and severe) as per Centers for disease control and prevention (CDC) criteria 2007. 2. Patients without any known systemic diseases \-
Exclusion criteria
1. Patients who have taken anti-inflammatory/antibiotic/antioxidant within 3 months of beginning of study. 2. Subjects who have undergone periodontal treatment within six months of inception of study. 3. Smokers, tobacco habits in any form and alcoholics. 4. Pregnant and lactating women. \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase | 1month |
| Aspartate aminotransferase | 1 month |
Secondary
| Measure | Time frame |
|---|---|
| sulcus bleeding index | 1month |
| plaque index | 1month |
| Clinical attachment loss | 1 month |
| probing depth | 1month |
| gingival index | 1 month |
Outcome results
None listed