Dermatitis, Atopic
Conditions
Brief summary
The current clinical guidelines for management of atopic dermatitis now recommend bleach baths. This requires simply the addition of regular household bleach to twice-weekly baths. At the Mayo Clinic, dilute acetic acid (vinegar) has been recommended for decades in wet wraps to treat patients hospitalized for their atopic dermatitis. However, this practice has not been widely adopted in the pediatric dermatology community. Will the use of dilute acetic acid (vinegar) in twice weekly baths help manage atopic dermatitis in pediatric patients as well as, or better than, the current accepted guidelines?
Interventions
OTHERBathing Additive
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
6 Months to 17 Years
Healthy volunteers
No
Inclusion criteria
1. Patients from 6 months to 17 years of age 2. Currently residing in US. 3. Follow up visits at 1 month, 3 months and 6 months after initiation of treatment in study (Figure 1). 4. Last follow-up at 1 year in clinic or via written mailed-out survey. 5. Diagnosis of atopic dermatitis AND 1. Have active signs of bacterial skin infection OR 2. Any documented suspected history of bacterial skin infection (weeping, crusting, and/or pustules on exam), OR 3. Prescription for oral antibiotics for skin infection in the past 6 months from any provider). OR 4. Have been prescribed bleach baths as part of an atopic dermatitis skin care regimen.
Exclusion criteria
1. Superficial skin infection without diagnosis of atopic dermatitis 2. Lack of in-clinic follow up assessment at 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EASI score at 6 months | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Courses of antibiotics required | 1 year |
Countries
United States
Outcome results
None listed