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Active Induction of Labor in Pregnancies Complicated With Oligohydramnios at Term

Management of Active Induction of Labor in Pregnancies Complicated With Oligohydramnios at Term; the Mode of Delivery and the Neonatal Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02581774
Enrollment
324
Registered
2015-10-21
Start date
2013-01-31
Completion date
2014-06-30
Last updated
2015-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oligohydramnios

Keywords

induction, cesarean delivery

Brief summary

The purpose of this study is to evaluate the risk of cesarean delivery in pregnancies complicated with isolated oligohydramnios managed by induction of labor. This prospective case-control study was conducted in Hamıdıye Sisli Etfal Teaching and Research Hospital between January 2013 and June 2014. 159 women with isolated oligohydramnios and 165 women with postdate pregnancies who met the inclusion criteria underwent induction of labor with dinoprostone or oxytocin. The rate and the indications of C/S deliveries were compared between two groups.

Detailed description

The study was designed as a prospective study. The rates of cesarean section and maternal/fetal outcomes had been compared between pregnancies complicated with isolated oligohydramnios at term and postdate pregnancies. All patients with isolated oligohydramnios were term (37-40 weeks' gestation according to accurate last menstrual period and first trimester sonographic examination). Oligohydramnios was defined as an amniotic fluid index \< 5 cm. The control group consisted of prolonged pregnancies in the absence of spontaneous labor and oligohydramnios. Prolonged pregnancy is diagnosed if 41 gestational weeks are completed according to accurate date of last menstrual period and first trimester ultrasound. All patients who accepted to join the study gave informed consent. All patients had a complete physical and obstetrical examination. Vital signs were recorded at regular intervals. The primary outcome measure was defined as cesarean section rates in pregnancies complicated with isolated oligohydramnios managed by induction of labor.

Interventions

OTHERnormal delivery tracking

normal delivery tracking

Sponsors

Sisli Hamidiye Etfal Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 44 Years
Healthy volunteers
Yes

Inclusion criteria

* term isolated oligohydramnios * postdate pregnancies * vertex presentation * singleton pregnancies * primigravid and multigravid women

Exclusion criteria

* women with presence of any chronic disease * maternal condition complicating the pregnancy

Design outcomes

Primary

MeasureTime frame
Cesarean rates in pregnancies complicated with isolated oligohydramniosup to 18 month

Secondary

MeasureTime frame
Fetal distress ratesup to 18 month
Number of patients (fetus) with 5-min Apgar score < 7up to 18 month
Number of patients with meconium stained amniotic fluidup to 18 month

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026