Effect of Intrathecal vs Intraarticular Dexmedetomidine on Postoperative Pain Following Arthroscopy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02581566

Enrollment

Registered

2015-10-21

Start date

2015-07-31

Completion date

2016-04-30

Last updated

2019-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Brief summary

Comparison between intrathecal Dexmedetomidine versus Intraarticular Dexmedetomidine on postoperative pain after knee arthroscopy.

Interventions

DRUGIntrathecal Dexmedetomidine

Addition of Intathecal Dexmedetomidine plus Intrathecal Bupivacaine

DRUGIntraarticular Dexmedetomidine

Addition of Intraarticular Dexmedetomidine plus Intrathecal Bupivacaine

DRUGBupivacaine

Intrathecal Bupivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Adult patients, ASA I-II, undergoing knee arthroscopy under spinal anesthesia.

Exclusion criteria

* Absolute or relative contraindications to spinal anesthesia, allergy to dexmedetomidine or chronic pain treatment.

Design outcomes

Primary

Measure	Time frame	Description
postoperative pain	24 hours	Assesment is done by Visual Analog Scale

Secondary

Measure	Time frame
c-reactive protein	24 hours

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026