Effect of Omega-3 Fatty Acids on Oxidative Stress and Dyslipidemia in Pediatric Patients Undergoing Hemodialysis

Evaluation of the Effect of Omega-3 Fatty Acids Supplementation on Pediatric Patients Undergoing Hemodialysis

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02581449

Enrollment

Registered

2015-10-21

Start date

2015-09-30

Completion date

2016-01-31

Last updated

2015-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Renal Disease

Keywords

omega-3 fatty acids, hemodialysis, oxidative stress, dyslipidemia

Brief summary

The purpose of the study is to evaluate the effect of omega-3 fatty acids supplementation on pediatric patients undergoing hemodialysis via the measurement of the following before and after omega-3 administration:oxidative stress markers, inflammatory markers and serum lipids.

Interventions

DIETARY_SUPPLEMENTomega-3

dietary supplement

OTHERempty soft gelatin capsules

empty softgels of matched size, shape and color

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

8 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Patients between 8 and 18 years old * Patients treated with HD for at least 6 months

Exclusion criteria

* Patients with malignancy and active inflammatory disease. * Patients who received vitamin E or any antioxidant treatment during the past 3 months.

Design outcomes

Primary

Measure	Time frame
effect on oxidative stress status via measurement of superoxide dismutase and glutathione peroxidase and malondialdehyde	four months

Secondary

Measure	Time frame
effect on serum lipid levels (HDL cholesterol, LDL cholesterol, total cholesterol, and triglycerides)	four months

Other

Measure	Time frame
effect on inflammation via measurement of C- Reactive Protein	four months
effect on nitric oxide (serum concentration)	four months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026