Esthesioneuroblastoma, Olfactory
Conditions
Keywords
Esthesioneuroblastoma, Tumor, Skull Base Surgery, Sinonasal Cancer
Brief summary
The purpose of this study is to collect and organize data into a repository to gather relevant information for future research from patients diagnosed with a rare malignant sinonasal cancer called esthesioneuroblastoma (ENB) and are scheduled to undergo endonasal skull base surgery. Data being collected includes surgical data, demographics, disease presentation, MRI, CT, PET imaging, and post-operative assessments including pathology tests. After surgery, the investigators will collect chemotherapy and radiation data. Participants will also complete quality of life questionnaires at their follow-up visits.
Interventions
None listed
Sponsors
Ricardo L. Carrau, MD
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
10 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Between the age of 10-80 years * Diagnosed with esthesioneuroblastoma
Exclusion criteria
* Refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Life | up to 120 months after treatment | Anterior Skull Base (ASB); Skull Base Inventory (SBI); Multidimensional Disease Specific Inventory MDS; ASB-Nasal 12; Sino-Nasal Outcome Test (SNOT-20) |
| Progression-free survival and overall survival | Up to 120 months | Kaplan-Meier survival curves |
Secondary
| Measure | Time frame |
|---|---|
| Length of Hospital Stay | up to 120 months |
| Time spent in operating room | up to 120 months |
| Number of participants with intraoperative complications | up to 120 months |
| Surgical Technique | up to 120 months |
| MRI imaging evidence of resection | up to 120 months |
| Number of participants with postoperative complications | up to 120 months |
Countries
United States
Outcome results
None listed