Anorexia Nervosa
Conditions
Keywords
Anorexia Nervosa, Exercise, Healthy Adults, Physical Activity
Brief summary
There are two major goals of this investigation. First, to develop pilot data to justify a larger randomized clinical trial of an intervention designed to train interoceptive signals (IS) and interoceptive responsivity (IR) in persons with Anorexia Nervosa (AN). Second, the investigators will determine whether persons with AN have similar or different IS and IR for heart rate while exercising as compared to age and gender matched controls.
Detailed description
The purpose of this pilot investigation is to assess AN interoceptive sensitivity and responsivity as it pertains to heart rate during exercise. Thirty adults, 18 years and older will be recruited for a cross-sectional comparison of IS and IR in the context of exercise.
Interventions
BEHAVIORALOne hour supervised exercise session
All participants will participate in a one hour supervised exercise session. Participants will wear a physical activity monitor during the assessment for continuous monitoring of heart rate. Short, intense bouts of exercise will be interspersed with rest periods.
Sponsors
Duke University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Study participants will include adults with anorexia spectrum disorders and healthy age and gender matched controls. There will be two control groups, one that includes regularly exercising age and gender matched persons and one where controls do not engage in regular exercise. For those with AN, the following INCLUSION criteria must be met: * Age ≥ 18 years old * BMI 25 kg/m2 or less * Diagnosis of anorexia spectrum disorder * Medications: Stable use of all medications ≥ three months For age and gender matched controls, the following INCLUSION criteria must be met: * Age ≥ 18 years old * BMI 25 kg/m2 or less * No diagnosis of anorexia spectrum disorder * Medications: Stable use of all medications ≥ three months * Age (+/- 2 years) and gender matched to study participant
Exclusion criteria
* History of diabetes, heart disease or taking medications for those conditions * History of hypertension (high blood pressure) not controlled with medication * Orthopedic limitations, musculoskeletal disease and/or injury * Inability to consent * Lack of transportation to the Duke Center for Living campus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean percentage of time in prescribed heart rate range during four bouts of interval exercise training | Baseline only | One exercise training session |
Countries
United States
Outcome results
None listed