Cervical Cancer, Cervical Intraepithelial Neoplasia
Conditions
Brief summary
Papanicolaou (Pap) triage, with high specificity, has been recommended for primary Human papillomavirus (HPV) testing but is flawed by poor sensitivity and cytologist dependence. the investigators evaluated the potential role of HPV Integration detection in cervical exfoliated cells in HPV-positive women from a clinic-based population.
Interventions
PROCEDURETCT，HPV，colposcopic inspection
Sponsors
Huazhong University of Science and Technology
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Women aged 30-65 years old visiting the gynecologic clinic of hospital
Exclusion criteria
1. Not providing informed consent 2. previously confirmed CIN, cervical cancer, or other malignancies 3. previous therapeutic procedure to cervix 4. pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and Specificity of the HPV integration screening test with comparison to HPV testing or TCT | 14 Months |
Countries
China
Contacts
Primary ContactDanhui Weng, MD, PhD
Outcome results
None listed