Cervical Cancer, Cervical Intraepithelial Neoplasia
Conditions
Brief summary
The primary objective is to determine the sensitivity and specificity of the HPV Integration-based cervical screening for detection of high-grade cervical intraepithelial neoplasia (CIN), using colposcopic inspection as the reference method. Lesions will be confirmed as malignant or CIN by colposcopic inspection and histopathologic examination.
Interventions
PROCEDURETCT，HPV，colposcopic inspection
Sponsors
Huazhong University of Science and Technology
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Women aged 30-65 years old Attending the China population-based organised cervical screening program
Exclusion criteria
1. Not providing informed consent 2. previously confirmed CIN, cervical cancer, or other malignancies 3. previous therapeutic procedure to cervix 4. pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the sensitivity and specificity of the HPV Integration-based cervical screening for detection of high-grade cervical intraepithelial neoplasia (CIN)with comparison to HPV testing or TCT | 14 Months |
Countries
China
Contacts
Primary ContactDanhui Weng, MD, PhD
Outcome results
None listed