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Epidemiology and Treatment Patterns of Paediatric PAH (Pulmonary Arterial Hypertension)

Study to Estimate the Incidence and Prevalence and Treatment Patterns of Pediatric Pulmonary Hypertension in the US

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02576002
Enrollment
2691
Registered
2015-10-15
Start date
2015-10-31
Completion date
2016-01-31
Last updated
2016-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Pulmonary

Keywords

Pulmonary Arterial Hypertension

Brief summary

To describe the prevalence, incidence and current treatment and procedures patterns in a US pediatric population with PAH in MarketScan database during the period 2010-2013

Interventions

DRUGAssigned pulmonary hypertension medication

As assigned by treating physician; may include following product classes: - Calcium channel blockers/antagonists - Prostanoids (prostaglandins, thromboxanes, prostacyclines) - Endothelin receptor antagonists - PDE-5 inhibitors - SGc stimulators

Sponsors

Bayer
Lead SponsorINDUSTRY

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

* All PAH patients who were in the MarketScan database and who were under age 18 at some time during the years 2010 through 2013

Exclusion criteria

Not applicable

Design outcomes

Primary

MeasureTime frame
Incidence rate of PAH (pulmonary arterial hypertension)Retrospective analysis of three year period
Prevalence rate of PAHRetrospective analysis of three year period

Secondary

MeasureTime frameDescription
Assigned drug treatment for PAH measured using the MarketScan databaseRetrospective analysis of three year periodDescription of pulmonary hypertension-targeted drugs prescribed in the study population and changes during the study period
Diagnostic procedures performed among PAH patients measured using the MarketScan databaseRetrospective analysis of three year period
Prevalence of comorbidities among PAH patientsRetrospective analysis of three year period

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026