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Old Blood and Postoperative Complications

The Effects of Old Red Blood Cell Transfusion on Morbidity in Patients Undergoing Revision Total Hip Arthroplasty: Retrospective Study

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02575820
Enrollment
0
Registered
2015-10-15
Start date
2015-11-30
Completion date
2016-05-31
Last updated
2016-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedics, Postoperative Complications, Red Blood Cells

Brief summary

The investigators sought to examine the effects of 'old' red blood cells on mortality and morbidity of patients who undergoing revision hip replacement arthroplasty. The investigators hypothesis is that patients have an increased risk of mortality and infection after 'old' red blood cells transfusions compared with those who received 'new' transfusions.

Interventions

PROCEDUREOld red blood cells transfusion

Red blood cells (shelf life \> 14 days) transfusion during the operation (total hip replacement arthroplasty)

PROCEDURENew red blood cells transfusion

Red blood cells (shelf life =\< 14 days) transfusion during the operation (total hip replacement arthroplasty)

Sponsors

Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who underwent revision total hip replacement

Exclusion criteria

* Patients who were not given red blood cells * Patients who were given two units of which one unit was old and one was new

Design outcomes

Primary

MeasureTime frame
Mortalitypostoperative 7 days
Sepsispostoperative 7 days
Wound infectionpostoperative 7 days
Postoperative deliriumpostoperative 7 days
Postoperative bleedingpostoperative 7 days

Secondary

MeasureTime frame
Renal failurepostoperative 7 days
Transfusion related lung injurypostoperative 7 days
Hepatic failurepostoperative 7 days
Pulmonary edemapostoperative 7 days
Pulmonary effusionpostoperative 7 days
Myocardial ischemiapostoperative 7 days
Pulmonary thromboembolismpostoperative 7 days

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026