Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02575716

Enrollment

Registered

2015-10-15

Start date

2013-03-31

Completion date

2014-03-31

Last updated

2015-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Relaxant

Keywords

McGrath®, Videolaryngoscope, intubating condition, muscle relaxant, intubation

Brief summary

The objective of this study was to evaluate intubating condition using the McGrath® VL Series 5, with and without muscle relaxant

Detailed description

Thirty-four patients with ASA classification I-II, who required oroendotracheal tube intubation, were studied in this prospective, double-blinded, randomized, clinical trial. Anesthesia was induced using fentanyl 1.5 mcg/kg, xylocaine 1.5 mg/kg and propofol 3 mg/kg. Patients were randomly assigned to one of the two groups to receive either rocuronium 0.6 mg/kg or saline intravenously. The Mcgrath® VL intubation was initiated after 90s, when the patients were fully relaxed. The primary outcome was to compare tracheal intubating conditions between two groups. The secondary outcomes were the success rate in the first attempt intubation, time to intubation, the required propofol dose for intubation and anesthetic complications. Statistical analyses were performed using the R program version 2.14.2. The level of statistical significance was set at p \< 0.05.

Interventions

DEVICEVideolaryngoscope

Intubation with McGrath video laryngoscope after muscle relaxant

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Age 18-65 years old. * ASA class I-II. * Elective surgery required general anesthesia with oroendotracheal intubation

Exclusion criteria

* Suspected or known difficult airway. * Patient with risk of aspiration with required of rapid sequence induction . * Plan remained intubation. * Allergic to drugs used in the study. * Renal or hepatic disease.

Design outcomes

Primary

Measure	Time frame	Description
Intubating condition.	one year	number of participants with 34 people

Secondary

Measure	Time frame
Success rate in the first attempt intubation.	one year
Time to intubation	One year
The required propofol dose for intubation without muscle relaxant.	one year
Events during the intubation attempts occurred.	one year

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026