Hepatitis C
Conditions
Brief summary
The study consists to Identify viral variants involved in the transmission of hepatitis C and characterize the antigenic and functional properties of their envelope glycoproteins at very early stage of infection (before seroconversion).
Interventions
PROCEDUREBlood sample (act specific of blood withdrawal for the study)
Specific intervention : blood sample (3x7 ml in total)
Sponsors
University Hospital, Tours
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 18 years * agree to participate in this study (signing the consent form or information form signed and letter of no objection for subjects contaminated by blood exposure). These criteria are specific to contaminated subjects: * primary infection before development of HCV antibody (seroconversion): nucleic acid testing positive in the absence of HCV antibodies. These criteria are specific to individual sources : * HCV antibody positive.
Exclusion criteria
* refusal to participate * private about freedom * under guardianship * under justice * minor or major person unable to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HCV serological markers | up to 30 months | Immunoblot analysis from blood samples collected during the study |
Countries
France
Outcome results
None listed