Orthopedics
Conditions
Brief summary
Delirium are common after orthopedic surgery in the elderly and are directly associated with loss of independence, reduction in the quality of life and increased mortality. The cause of postoperative delirium still remains unclear and may be multifactorial. The aim of this retrospective study is to examine prevalence of postoperative delirium according to the use of dexmedetomidine or propofol in elderly patients undergoing orthopedic surgery under regional anesthesia.
Interventions
DRUGDexmedetomidine
DRUGPropofol
Sponsors
Seoul National University Bundang Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who underwent orthopedic surgery under regional anesthesia * age of 65 years or greater
Exclusion criteria
* General anesthesia * age \< 65 years * central nervous system disease, including dementia and Parkinson's disease * Patients who were not received sedation with propofol or dexmedetomidine during the operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| delirium | within 7 day postoperatively |
Secondary
| Measure | Time frame |
|---|---|
| Wound infection | within 7 day postoperatively |
| Pulmonary thromboembolism | within 7 day postoperatively |
| Hospital stay | through study completion, an average of 7days |
Other
| Measure | Time frame |
|---|---|
| Renal failure | within 7 day postoperatively |
| Hepatic failure | within 7 day postoperatively |
| Myocardial ischemia | within 7 day postoperatively |
Countries
South Korea
Outcome results
None listed