Air Pollution and Cardiovascular Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02573103

Enrollment

Registered

2015-10-09

Start date

2014-11-30

Completion date

2016-01-31

Last updated

2018-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic Disorder

Brief summary

To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.

Exclusion criteria

* Screening visit BP\>140/90 mm Hg, fasting glucose \>126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.

Design outcomes

Primary

Measure	Time frame	Description
Dyslipidemia	One year	Analyzed HDL by Beckman AU5800

Secondary

Measure	Time frame	Description
System oxidative stress	One year	Analyzed oxidative stress biomarkers,such as MDA by HPLC

Outcome results