Acinetobacter Infections
Conditions
Brief summary
The present study was designed to study the impact of empirical treatment with colistin empirical monotherapy and combined treatment with tigecycline and vancomycin on mortality of bacteremia Multiresistant Acinetobacter Baumannii . The main objective was to evaluate the efficacy of empirical treatment with colistin and combined targeted therapy. The different therapeutical interventions were administered following the routine clinical practice in the medical centre and the investigator did not assign specific interventions to the subjects of the study.
Interventions
DRUGColistin
DRUGTigecycline
DRUGVancomycin
Sponsors
Maimónides Biomedical Research Institute of Córdoba
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Critics included patients ≥ 16 years with monomicrobial bloodstream infections by multiresistant acinetobacter baumannii to carbapenems and sensitive to colistin accompanied by systemic inflammatory response syndrome, provided they have received targeted treatment with colistin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause 30-day mortality (crude). | 30 days |
Secondary
| Measure | Time frame |
|---|---|
| All-cause 14 day mortality (crude). | 14 days |
Outcome results
None listed