Ultrasonographic Reference Values for Peripheral Nerves in Children

Ultrasonographic Reference Values for Peripheral Nerves and Nerve Roots in the Normal Population of Children and Adolescents

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02570802

Enrollment

255

Registered

2015-10-07

Start date

2015-10-31

Completion date

2024-12-31

Last updated

2024-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal Values of Peripheral Nerves in Healthy Children

Brief summary

The purpose of this clinical trial is to assess normal values of the cross-sectional area of peripheral nerves and nerve roots in children and adolescents between 2 and 18 years.

Detailed description

This is a single center prospective clinical trial to determine standard values of the cross-sectional area of the median, ulnar, radial, peroneal, tibial, sural and vagus nerve as well as C5, C6 and C7 cervical roots in a cohort of neuromuscular unaffected children and adolescents between 2 and 18 years.

Interventions

PROCEDUREUltrasonographic examination

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to 18 Years

Healthy volunteers

Yes

Inclusion criteria

* Children and adolescents between 2 and 18 years * Written informed consent of the caregivers and the children/adolescents between 14 and 18 years

Exclusion criteria

* Inability to meet study requirements * Neuromuscular disease or symptoms

Design outcomes

Primary

Measure	Time frame	Description
Cross-sectional area (mm2) of the sural nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the peroneal nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the tibial nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the vagus nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the C5 cervical root in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the C6 cervical root in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the C7 cervical root in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the radial nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length
Cross-sectional area (mm2) of the superficial radial nerve in children and adolescents from 2 to 18 years	one year	Cross-sectional area will be displayed as percentiles according age, weight and length

Secondary

Measure	Time frame	Description
Intrarater reliability	one year	Reliability is expressed by the intraclass correlation coefficient (ICC)
Interrater reliability	one year	Reliability is expressed by the intraclass correlation coefficient (ICC)

Countries

Switzerland

Contacts

Primary ContactPatricia Hafner, MD

patricia.hafner@ukbb.ch+41617042272

Backup ContactMaria Rasenack, MD

maria.rasenack@usb.ch+41612652525

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026