Acellular Pertussis, Aspergillosis, Allergic Bronchopulmonary, Diphtheria, Diphtheria-Tetanus-acellular Pertussis Vaccines, Tetanus
Conditions
Keywords
Boostrix™, Bagota, maternal vaccination, Pertussis, Mortality, Morbidity
Brief summary
This study is being conducted to assess impact of maternal immunisation against pertussis in infants ≤12 months of age before and after introduction of pertussis maternal immunisation in Bogota, Colombia from January 2005-December 2014.
Detailed description
An observational, retrospective, ecological database study which involves systematic screening of the national databases of Bogota, to study pertussis related morbidity and mortality in infants ≤ 12 months of age before and after introduction of pertussis maternal immunisation in Bogota, Colombia from January 2005-December 2014.
Interventions
OTHERPertussis maternal immunization
Retrospective time trend analysis before and after pertussis maternal immunization in Bogota, Colombia.
Sponsors
GlaxoSmithKline
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Days to 12 Months
Healthy volunteers
No
Inclusion criteria
• Not applicable as since this retrospective database study will include all the available aggregated data of pertussis cases, pertussis related hospitalisations and deaths, ALRTI cases, primary pertussis vaccination coverage and Boostrix vaccination coverage.
Exclusion criteria
• Not applicable as since this retrospective database study will include all the available aggregated data of pertussis cases, pertussis related hospitalisations and deaths, ALRTI cases, primary pertussis vaccination coverage and Boostrix vaccination coverage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of reported cases of hospitalisations and deaths due to pertussis in infants ≤6 weeks of age, in post-vaccination period compared to pre-vaccination period of Boostrix vaccination | During the 9-year period (January 2005- December 2014) |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of reported cases of hospitalisations and deaths due to pertussis in infants 7 weeks to ≤12 months of age, in post-vaccination period compared to pre-vaccination period of Boostrix vaccination | During the 9-year period (January 2005- December 2014) |
| Occurrence of ALRTI in infants ≤6 weeks of age and 7 weeks to ≤12 months of age, following the introduction of pertussis maternal immunisation in Bogota, Colombia | During the 9-year period (January 2005- December 2014) |
| Description of the total number of doses of Boostrix administered in pregnant women, after its introduction into the UMV program in Bogota | During the 9-year period (January 2005- December 2014) |
| Description of the total number of doses of primary pertussis vaccine administered to infants ≤12 months of age in Bogota | During the 9-year period (January 2005- December 2014) |
Countries
Colombia
Outcome results
None listed